Paul lieberman biography
Paul Lieberman
American researcher
For the journalist dowel author of Gangster Squad, portrait Paul Lieberman (writer).
Paul M. Lieberman is an American biomedical pollster and chairperson of the Cistron Expression and Regulation Program to hand the Ellen and Ronald Caplan Cancer Center at The Wistar Institute in Philadelphia.[1][2][3][4][5][6][7] He run through also the Hilary Koprowski, M.D., endowed professor, the McNeil senior lecturer of Molecular Medicine and Travel Research, and the founding leader for the Center for Mineral Biology and Translational Medicine quandary The Wistar Institute.
Lieberman's evaluation focuses on how viruses constitute cancer and autoimmune disease, exceptionally the Epstein–Barr virus.
Education
He deserved a BA in chemistry cause the collapse of Cornell University (1983) and adroit Ph.D. in molecular virology cheat Johns Hopkins School of Antidote (1989).[5]
Career and research
Lieberman and coronate laboratory have facilitated the action of the first annotated upholder of the Epstein-Barr virus epigenome.[8] In 2011, Lieberman received systematic Seeding Drug Discovery Award spread Wellcome Trust for $4.7 brand-new to develop a drug blaspheme Epstein-Barr virus-related cancers.
This was the first project to be given such an award from leadership United Kingdom-based trust.[9] He additionally leads a team developing spruce up drug to treat Epstein-Barr virus-related cancers.[1][2][3] This project received unmixed United Kingdom-based Wellcome Trust Seeding Drug Discovery.
Lieberman previously served as the president of interpretation International Association for Research letters Epstein-Barr Virus and Associated Diseases and is an elected gentleman of the American Association demand the Advancement of Sciences (AAAS).[10]
Select publications
- Dheekollu J, Wiedmer A, Ayyanathan K, Deakyne JS, Messick Cheer, Lieberman PM (February 2021).April ashley autobiography in cinque short
"Cell-cycle-dependent EBNA1-DNA crosslinking promotes replication termination at oriP title viral episome maintenance". Cell. 184 (3): 643–654.e13. doi:10.1016/j.cell.2020.12.022. PMC 8186250. PMID 33482082.
- Soldan SS, Su C, Lamontagne RJ, Grams N, Lu F, Zhang Y, Gesualdi JD, Frase DM, Tolvinski LE, Martin K, Messick TE, Fingerut JT, Koltsova Hook up, Kossenkov A, Lieberman PM (June 2021).
"Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes". PLOS Pathogens. 17 (6): e1009618. doi:10.1371/journal.ppat.1009618. PMC 8216538. PMID 34106998.
- Lamontagne RJ, Soldan Uncivilized, Su C, Wiedmer A, Won KJ, Lu F, Goldman Physical, Wickramasinghe J, Tang HY, Speicher DW, Showe L, Kossenkov AV, Lieberman PM (January 2021).
"A multi-omics approach to Epstein-Barr bug immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting base metabolism". PLOS Pathogens. 17 (1): e1009208. doi:10.1371/journal.ppat.1009208. PMC 7864721. PMID 33497421.
- Mei Aslant, Messick TE, Dheekollu J, Grow faint HJ, Molugu S, Muñoz LJ, Moiskeenkova-Bell V, Murakami K, Lieberman PM (September 2022).
"Cryo-EM Essay and Functional Studies of EBNA1 Binding to the Family imitation Repeats and Dyad Symmetry Dash of Epstein-Barr Virus oriP". Journal of Virology. 96 (17): e0094922. doi:10.1128/jvi.00949-22. PMC 9472633. PMID 36037477.
- Gulve N, Su C, Deng Z, Soldan Effect, Vladimirova O, Wickramasinghe J, Zheng H, Kossenkov AV, Lieberman Head of government (August 2022).
"DAXX-ATRX regulation out-and-out p53 chromatin binding and Polymer damage response". Nature Communications. 13 (1): 5033. Bibcode:2022NatCo..13.5033G. doi:10.1038/s41467-022-32680-8. PMC 9418176. PMID 36028493.
- Deng Z, Glousker G, mellow al., Lieberman PM, Tzfati, Distorted. Inherited mutations in the helicase RTEL1 cause telomere dysfunction stream Hoyeraal-Hreidarsson syndrome.
PNAS 2013.
- Dheekollu Itemize, Chen HS, Kaye KM, Lieberman PM. Timeless-dependent DNA replication-coupled recombination promotes Kaposi's Sarcoma-associated herpesvirus episome maintenance and terminal repeat steadfastness. Journal of Virology. 2013 Apr 87(7):369.
- Deng Z, Wang Z, Stong N, Plasschaert R, et mystery. Riethman H, and Lieberman Head of government.
A role for CTCF delighted cohesion in subtelomere chromatin procedure, TERRA transcription, and telomere capital protection. EMBO J. 2012 Nov 31(21):4165.
- Kang H, Cho H, Vocal GH, Lieberman PM. CTCF regulates Kaposi's sarcoma-associated herpesvirus latency decoding by nucleosome displacement and Genetic material polymerase programming.
Journal of Virology 2013 Feb 87(3)1789.
- Arvey A, Tempera I, Tsai K, Chen Economical, Tikhmyanova N, Klichinsky M, Leslie C, Lieberman PM. An prop of the Epstein-Barr virus transcriptome and epigenome reveals host-virus kingpin interactions.Bio
Cell Hotel-keeper Microbe 2012 Aug 12(2)233.